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Metacell-2: a divide-and-conquer metacell algorithm for scalable scRNA-seq analysis
Scaling scRNA-seq to profile millions of cells is crucial for constructing high-resolution maps of transcriptional manifolds. Current analysis strategies, in particular dimensionality reduction and two-phase clustering, offer only limited scaling and sensitivity to define such manifolds. We introduc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9019975/ https://www.ncbi.nlm.nih.gov/pubmed/35440087 http://dx.doi.org/10.1186/s13059-022-02667-1 |