Determination and pharmacokinetics study of UK-5099 in mouse plasma by LC–MS/MS

BACKGROUND: UK-5099 is a potent mitochondrial acetone carrier inhibitor, that exhibits anticancer activity. Recently, the anti-Toxoplasma gondii activity of UK-5099 was proposed, and in vivo studies of its pharmacokinetics in BALB/c mice are necessary to further evaluate the clinical effect of UK-50...

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Detalles Bibliográficos
Autores principales: Zeng, Qingyuan, Si, Hongfei, Lv, Kun, Mo, Jiao, Wang, Xinnian, Yan, Biqing, Zhang, Jili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020015/
https://www.ncbi.nlm.nih.gov/pubmed/35443692
http://dx.doi.org/10.1186/s12917-022-03245-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020015/
https://www.ncbi.nlm.nih.gov/pubmed/35443692
http://dx.doi.org/10.1186/s12917-022-03245-0

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