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Determination and pharmacokinetics study of UK-5099 in mouse plasma by LC–MS/MS

BACKGROUND: UK-5099 is a potent mitochondrial acetone carrier inhibitor, that exhibits anticancer activity. Recently, the anti-Toxoplasma gondii activity of UK-5099 was proposed, and in vivo studies of its pharmacokinetics in BALB/c mice are necessary to further evaluate the clinical effect of UK-50...

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Detalles Bibliográficos
Autores principales:	Zeng, Qingyuan, Si, Hongfei, Lv, Kun, Mo, Jiao, Wang, Xinnian, Yan, Biqing, Zhang, Jili
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020015/ https://www.ncbi.nlm.nih.gov/pubmed/35443692 http://dx.doi.org/10.1186/s12917-022-03245-0

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