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PTHrP induces STAT5 activation, secretory differentiation and accelerates mammary tumor development

BACKGROUND: Parathyroid hormone-related protein (PTHrP) is required for embryonic breast development and has important functions during lactation, when it is produced by alveolar epithelial cells and secreted into the maternal circulation to mobilize skeletal calcium used for milk production. PTHrP...

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Detalles Bibliográficos
Autores principales: Grinman, Diego Y., Boras-Granic, Kata, Takyar, Farzin M., Dann, Pamela, Hens, Julie R., Marmol, Christina, Lee, Jongwon, Choi, Jungmin, Chodosh, Lewis A., Sola, Martin E. Garcia, Wysolmerski, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020078/
https://www.ncbi.nlm.nih.gov/pubmed/35440032
http://dx.doi.org/10.1186/s13058-022-01523-1