Cargando…
PTHrP induces STAT5 activation, secretory differentiation and accelerates mammary tumor development
BACKGROUND: Parathyroid hormone-related protein (PTHrP) is required for embryonic breast development and has important functions during lactation, when it is produced by alveolar epithelial cells and secreted into the maternal circulation to mobilize skeletal calcium used for milk production. PTHrP...
Autores principales: | Grinman, Diego Y., Boras-Granic, Kata, Takyar, Farzin M., Dann, Pamela, Hens, Julie R., Marmol, Christina, Lee, Jongwon, Choi, Jungmin, Chodosh, Lewis A., Sola, Martin E. Garcia, Wysolmerski, John J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020078/ https://www.ncbi.nlm.nih.gov/pubmed/35440032 http://dx.doi.org/10.1186/s13058-022-01523-1 |
Ejemplares similares
-
Deletion of the Nuclear Localization Sequences and C-Terminus of PTHrP Impairs Embryonic Mammary Development but also Inhibits PTHrP Production
por: Boras-Granic, Kata, et al.
Publicado: (2014) -
PTHrP and breast cancer: more than hypercalcemia and bone metastases
por: Boras-Granic, Kata, et al.
Publicado: (2012) -
Embryonic cells contribute directly to the quiescent stem cell population in the adult mouse mammary gland
por: Boras-Granic, Kata, et al.
Publicado: (2014) -
A Case of Hypercalcemia from PTHrP-Producing Fibromyxoid Sarcoma Responsive to Glucocorticoid Therapy
por: Niu, Isabella, et al.
Publicado: (2023) -
PSAT208 A Case of Hypercalcemia From PTHrP-Producing Fibromyxoid Sarcoma Responsive to Glucocorticoid Therapy
por: Niu, Isabella, et al.
Publicado: (2022)