Cargando…

Integrative analysis of therapy resistance and transcriptomic profiling data in glioblastoma cells identifies sensitization vulnerabilities for combined modality radiochemotherapy

BACKGROUND: Inherent resistance to radio/chemotherapy is one of the major reasons for early recurrence, treatment failure, and dismal prognosis of glioblastoma. Thus, the identification of resistance driving regulators as prognostic and/or predictive markers as well as potential vulnerabilities for...

Descripción completa

Detalles Bibliográficos
Autores principales: Schnöller, Leon Emanuel, Albrecht, Valerie, Brix, Nikko, Nieto, Alexander Edward, Fleischmann, Daniel Felix, Niyazi, Maximilian, Hess, Julia, Belka, Claus, Unger, Kristian, Lauber, Kirsten, Orth, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020080/
https://www.ncbi.nlm.nih.gov/pubmed/35440003
http://dx.doi.org/10.1186/s13014-022-02052-z