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Integrative analysis of therapy resistance and transcriptomic profiling data in glioblastoma cells identifies sensitization vulnerabilities for combined modality radiochemotherapy
BACKGROUND: Inherent resistance to radio/chemotherapy is one of the major reasons for early recurrence, treatment failure, and dismal prognosis of glioblastoma. Thus, the identification of resistance driving regulators as prognostic and/or predictive markers as well as potential vulnerabilities for...
Autores principales: | Schnöller, Leon Emanuel, Albrecht, Valerie, Brix, Nikko, Nieto, Alexander Edward, Fleischmann, Daniel Felix, Niyazi, Maximilian, Hess, Julia, Belka, Claus, Unger, Kristian, Lauber, Kirsten, Orth, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020080/ https://www.ncbi.nlm.nih.gov/pubmed/35440003 http://dx.doi.org/10.1186/s13014-022-02052-z |
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