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Addressing the role of PKD3 in the T cell compartment with knockout mice

BACKGROUND: The Protein kinase D3 (PKD3) has been implicated in signal transduction downstream of the T cell receptor (TCR). However, its role for the activation of primary T lymphocytes has not been elucidated so far. METHODS: Expression of PKD isoforms in primary murine T cells was determined by R...

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Detalles Bibliográficos
Autores principales: Koutník, Jiří, Neururer, Verena, Gruber, Thomas, Peer, Sebastian, Hermann-Kleiter, Natascha, Olson, William J., Labi, Verena, Leitges, Michael, Baier, Gottfried, Siegmund, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020081/
https://www.ncbi.nlm.nih.gov/pubmed/35440091
http://dx.doi.org/10.1186/s12964-022-00864-w