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SPARC: Structural properties associated with residue constraints

SPARC facilitates the generation of plausible hypotheses regarding underlying biochemical mechanisms by structurally characterizing protein sequence constraints. Such constraints appear as residues co-conserved in functionally related subgroups, as subtle pairwise correlations (i.e., direct coupling...

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Detalles Bibliográficos
Autores principales: Neuwald, Andrew F., Yang, Hui, Tracy Nixon, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020082/
https://www.ncbi.nlm.nih.gov/pubmed/35495120
http://dx.doi.org/10.1016/j.csbj.2022.04.005