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Gut microbiome-derived glycine lipids are diet-dependent modulators of hepatic injury and atherosclerosis

Oral and gut Bacteroidetes produce unique classes of serine-glycine lipodipeptides and glycine aminolipids that signal through host Toll-like receptor 2. These glycine lipids have also been detected in human arteries, but their effects on atherosclerosis are unknown. Here, we sought to investigate t...

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Detalles Bibliográficos
Autores principales: Millar, Courtney L., Anto, Liya, Garcia, Chelsea, Kim, Mi-Bo, Jain, Anisha, Provatas, Anthony A., Clark, Robert B., Lee, Ji-Young, Nichols, Frank C., Blesso, Christopher N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020096/
https://www.ncbi.nlm.nih.gov/pubmed/35278409
http://dx.doi.org/10.1016/j.jlr.2022.100192