Modeling Patient-Specific Muscular Dystrophy Phenotypes and Therapeutic Responses in Reprogrammed Myotubes Engineered on Micromolded Gelatin Hydrogels

In vitro models of patient-derived muscle allow for more efficient development of genetic medicines for the muscular dystrophies, which often present mutation-specific pathologies. One popular strategy to generate patient-specific myotubes involves reprogramming dermal fibroblasts to a muscle lineag...

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Detalles Bibliográficos
Autores principales: Barthélémy, Florian, Santoso, Jeffrey W., Rabichow, Laura, Jin, Rongcheng, Little, Isaiah, Nelson, Stanley F., McCain, Megan L., Miceli, M. Carrie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020228/
https://www.ncbi.nlm.nih.gov/pubmed/35465312
http://dx.doi.org/10.3389/fcell.2022.830415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020228/
https://www.ncbi.nlm.nih.gov/pubmed/35465312
http://dx.doi.org/10.3389/fcell.2022.830415

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