Recent Advances in the Development of Non-PIKKs Targeting Small Molecule Inhibitors of DNA Double-Strand Break Repair

The vast majority of cancer patients receive DNA-damaging drugs or ionizing radiation (IR) during their course of treatment, yet the efficacy of these therapies is tempered by DNA repair and DNA damage response (DDR) pathways. Aberrations in DNA repair and the DDR are observed in many cancer subtype...

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Detalles Bibliográficos
Autores principales: Kelm, Jeremy M., Samarbakhsh, Amirreza, Pillai, Athira, VanderVere-Carozza, Pamela S., Aruri, Hariprasad, Pandey, Deepti S., Pawelczak, Katherine S., Turchi, John J., Gavande, Navnath S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020266/
https://www.ncbi.nlm.nih.gov/pubmed/35463312
http://dx.doi.org/10.3389/fonc.2022.850883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020266/
https://www.ncbi.nlm.nih.gov/pubmed/35463312
http://dx.doi.org/10.3389/fonc.2022.850883

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