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IBD Subtype-Regulators IFNG and GBP5 Identified by Causal Inference Drive More Intense Innate Immunity and Inflammatory Responses in CD Than Those in UC

Background: The pathological differences between Crohn’s disease (CD) and ulcerative colitis (UC) are substantial and unexplained yet. Here, we aimed to identify potential regulators that drive different pathogenesis of CD and UC by causal inference analysis of transcriptome data. Methods: Kruskal–W...

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Detalles Bibliográficos
Autores principales: Gao, Sheng, Li, Yichen, Wu, Dingfeng, Jiao, Na, Yang, Li, Zhao, Rui, Xu, Zhifeng, Chen, Wanning, Lin, Xutao, Cheng, Sijing, Zhu, Lixin, Lan, Ping, Zhu, Ruixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020454/
https://www.ncbi.nlm.nih.gov/pubmed/35462887
http://dx.doi.org/10.3389/fphar.2022.869200