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Highly polymerized proanthocyanidins (PAC) components from blueberry leaf and stem significantly inhibit SARS-CoV-2 infection via inhibition of ACE2 and viral 3CLpro enzymes

With the current worldwide pandemic of COVID-19, there is an urgent need to develop effective treatment and prevention methods against SARS-CoV-2 infection. We have previously reported that the proanthocyanidin (PAC) fraction in blueberry (BB) leaves has strong antiviral activity against hepatitis C...

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Detalles Bibliográficos
Autores principales: Sugamoto, Kazuhiro, Tanaka, Yuri L., Saito, Akatsuki, Goto, Yoh, Nakayama, Takayuki, Okabayashi, Tamaki, Kunitake, Hisato, Morishita, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020496/
https://www.ncbi.nlm.nih.gov/pubmed/35605406
http://dx.doi.org/10.1016/j.bbrc.2022.04.072