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Epac1 activation by cAMP regulates cellular SUMOylation and promotes the formation of biomolecular condensates
Protein SUMOylation plays an essential role in maintaining cellular homeostasis when cells are under stress. However, precisely how SUMOylation is regulated, and a molecular mechanism linking cellular stress to SUMOylation, remains elusive. Here, we report that cAMP, a major stress-response second m...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020664/ https://www.ncbi.nlm.nih.gov/pubmed/35442725 http://dx.doi.org/10.1126/sciadv.abm2960 |