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A somatic mutation in moesin drives progression into acute myeloid leukemia

Acute myeloid leukemia (AML) arises when leukemia-initiating cells, defined by a primary genetic lesion, acquire subsequent molecular changes whose cumulative effects bypass tumor suppression. The changes that underlie AML pathogenesis not only provide insights into the biology of transformation but...

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Detalles Bibliográficos
Autores principales: Yuan, Ouyang, Ugale, Amol, de Marchi, Tommaso, Anthonydhason, Vimala, Konturek-Ciesla, Anna, Wan, Haixia, Eldeeb, Mohamed, Drabe, Caroline, Jassinskaja, Maria, Hansson, Jenny, Hidalgo, Isabel, Velasco-Hernandez, Talia, Cammenga, Jörg, Magee, Jeffrey A., Niméus, Emma, Bryder, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020775/
https://www.ncbi.nlm.nih.gov/pubmed/35442741
http://dx.doi.org/10.1126/sciadv.abm9987