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Mechanism of stress-induced attacks in an episodic neurologic disorder

Stress is the most common trigger among episodic neurologic disorders. In episodic ataxia type 2 (EA2), physical or emotional stress causes episodes of severe motor dysfunction that manifest as ataxia and dystonia. We used the tottering (tg/tg) mouse, a faithful animal model of EA2, to dissect the m...

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Detalles Bibliográficos
Autores principales: Snell, Heather D., Vitenzon, Ariel, Tara, Esra, Chen, Chris, Tindi, Jaafar, Jordan, Bryen A., Khodakhah, Kamran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020779/
https://www.ncbi.nlm.nih.gov/pubmed/35442745
http://dx.doi.org/10.1126/sciadv.abh2675