RRx-001 Exerts Neuroprotection Against LPS-Induced Microglia Activation and Neuroinflammation Through Disturbing the TLR4 Pathway

Neuroinflammation plays an important role in the pathogenesis of many central nervous system diseases. Here, we investigated the effect of an anti-cancer compound RRx-001 on neuroinflammation and its possible new applications. BV2 cells and primary microglia cells were used to evaluate the role of R...

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Detalles Bibliográficos
Autores principales: Fang, Jie, She, Jing, Lin, Fang, Wu, Jun-Chao, Han, Rong, Sheng, Rui, Wang, Guanghui, Qin, Zheng-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020799/
https://www.ncbi.nlm.nih.gov/pubmed/35462935
http://dx.doi.org/10.3389/fphar.2022.889383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020799/
https://www.ncbi.nlm.nih.gov/pubmed/35462935
http://dx.doi.org/10.3389/fphar.2022.889383

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