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Colicin E1 opens its hinge to plug TolC

The double membrane architecture of Gram-negative bacteria forms a barrier that is impermeable to most extracellular threats. Bacteriocin proteins evolved to exploit the accessible, surface-exposed proteins embedded in the outer membrane to deliver cytotoxic cargo. Colicin E1 is a bacteriocin produc...

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Detalles Bibliográficos
Autores principales: Budiardjo, S Jimmy, Stevens, Jacqueline J, Calkins, Anna L, Ikujuni, Ayotunde P, Wimalasena, Virangika K, Firlar, Emre, Case, David A, Biteen, Julie S, Kaelber, Jason T, Slusky, Joanna SG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020818/
https://www.ncbi.nlm.nih.gov/pubmed/35199644
http://dx.doi.org/10.7554/eLife.73297