Molecular determinants of complexin clamping and activation function

Previously we reported that Synaptotagmin-1 and Complexin synergistically clamp the SNARE assembly process to generate and maintain a pool of docked vesicles that fuse rapidly and synchronously upon Ca(2+) influx (Ramakrishnan et al., 2020). Here, using the same in vitro single-vesicle fusion assay,...

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Detalles Bibliográficos
Autores principales: Bera, Manindra, Ramakrishnan, Sathish, Coleman, Jeff, Krishnakumar, Shyam S, Rothman, James E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020821/
https://www.ncbi.nlm.nih.gov/pubmed/35442188
http://dx.doi.org/10.7554/eLife.71938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020821/
https://www.ncbi.nlm.nih.gov/pubmed/35442188
http://dx.doi.org/10.7554/eLife.71938

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