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Molecular determinants of complexin clamping and activation function
Previously we reported that Synaptotagmin-1 and Complexin synergistically clamp the SNARE assembly process to generate and maintain a pool of docked vesicles that fuse rapidly and synchronously upon Ca(2+) influx (Ramakrishnan et al., 2020). Here, using the same in vitro single-vesicle fusion assay,...
Autores principales: | Bera, Manindra, Ramakrishnan, Sathish, Coleman, Jeff, Krishnakumar, Shyam S, Rothman, James E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020821/ https://www.ncbi.nlm.nih.gov/pubmed/35442188 http://dx.doi.org/10.7554/eLife.71938 |
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