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DNA circles promote yeast ageing in part through stimulating the reorganization of nuclear pore complexes

The nuclear pore complex (NPC) mediates nearly all exchanges between nucleus and cytoplasm, and in many species, it changes composition as the organism ages. However, how these changes arise and whether they contribute themselves to ageing is poorly understood. We show that SAGA-dependent attachment...

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Detalles Bibliográficos
Autores principales: Meinema, Anne C, Marzelliusardottir, Anna, Mirkovic, Mihailo, Aspert, Théo, Lee, Sung Sik, Charvin, Gilles, Barral, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020822/
https://www.ncbi.nlm.nih.gov/pubmed/35373738
http://dx.doi.org/10.7554/eLife.71196