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Scorpion Venom Polypeptide Inhibits Pulmonary Epithelial-Mesenchymal Transition in Systemic Sclerosis-Interstitial Lung Disease Model Mice by Intervening TGF-β1/Smad Signaling Pathway

OBJECTIVE: Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc). The aim of this study was to investigate the effect and possible mechanism of polypeptide extract of scorpion venom (PESV) on SSc-ILD. METHODS: C57/BL6 mice were injected with bleomycin to establish...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Xu, Liping, Chen, Qiang, Guan, Tianrong, Lin, Na, Xu, Danyang, Lu, Lihong, Dai, Qiaoding, Song, Xinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020946/
https://www.ncbi.nlm.nih.gov/pubmed/35463079
http://dx.doi.org/10.1155/2022/6557486