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Inhibition of PARP Potentiates Immune Checkpoint Therapy through miR-513/PD-L1 Pathway in Hepatocellular Carcinoma

BACKGROUND: The DNA repair enzyme poly(ADP-ribose) polymerase (PARP) is involved in DNA damage repair and cell death. However, the association between PARP's biological activities and the immune microenvironment in hepatocellular carcinoma (HCC) is unclear. The present study will explore whethe...

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Detalles Bibliográficos
Autores principales: Sun, Guoqiang, Miao, Ganggang, Li, Zhitao, Zheng, Wubin, Zhou, Chunguang, Sun, Guangshun, Cao, Hongyong, Li, Zhouxiao, Tang, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020948/
https://www.ncbi.nlm.nih.gov/pubmed/35466317
http://dx.doi.org/10.1155/2022/6988923