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Nur77 Deficiency Exacerbates Macrophage NLRP3 Inflammasome-Mediated Inflammation and Accelerates Atherosclerosis

PURPOSE: Activation of NLR (nucleotide-binding and leucine-rich repeat immune receptor) family pyrin domain containing 3 (NLRP3) inflammasome mediating interleukin- (IL-) 1β secretion has emerged as an important component of inflammatory processes in atherogenesis. The nuclear receptor Nur77 is high...

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Detalles Bibliográficos
Autores principales: Yuan, Ruosen, Zhang, Weifeng, Nie, Peng, Lan, Keke, Yang, Xiaoxiao, Yin, Anwen, Xiao, Qingqing, Shen, Yejiao, Xu, Ke, Wang, Xia, Pan, Xin, Shen, Linghong, He, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020982/
https://www.ncbi.nlm.nih.gov/pubmed/35464766
http://dx.doi.org/10.1155/2022/2017815