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Nonlinear control of transcription through enhancer–promoter interactions
Chromosome structure in mammals is thought to regulate transcription by modulating three-dimensional interactions between enhancers and promoters, notably through CTCF-mediated loops and topologically associating domains (TADs)(1–4). However, how chromosome interactions are actually translated into...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021019/ https://www.ncbi.nlm.nih.gov/pubmed/35418676 http://dx.doi.org/10.1038/s41586-022-04570-y |