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Nonlinear control of transcription through enhancer–promoter interactions

Chromosome structure in mammals is thought to regulate transcription by modulating three-dimensional interactions between enhancers and promoters, notably through CTCF-mediated loops and topologically associating domains (TADs)(1–4). However, how chromosome interactions are actually translated into...

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Detalles Bibliográficos
Autores principales: Zuin, Jessica, Roth, Gregory, Zhan, Yinxiu, Cramard, Julie, Redolfi, Josef, Piskadlo, Ewa, Mach, Pia, Kryzhanovska, Mariya, Tihanyi, Gergely, Kohler, Hubertus, Eder, Mathias, Leemans, Christ, van Steensel, Bas, Meister, Peter, Smallwood, Sebastien, Giorgetti, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021019/
https://www.ncbi.nlm.nih.gov/pubmed/35418676
http://dx.doi.org/10.1038/s41586-022-04570-y