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SARS-CoV-2 mutations acquired during serial passage in human cell lines are consistent with several of those found in recent natural SARS-CoV-2 variants

Since the outbreak of coronavirus disease (COVID-19) in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved into diverse variants. Here, an early isolate of SARS-CoV-2 was serially passaged in multiple cell lines of human origin in triplicate, and selected mutations were c...

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Detalles Bibliográficos
Autores principales: Chung, Hoyin, Noh, Ji Yeong, Koo, Bon-Sang, Hong, Jung Joo, Kim, Hye Kwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021118/
https://www.ncbi.nlm.nih.gov/pubmed/35474907
http://dx.doi.org/10.1016/j.csbj.2022.04.022