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Mitochondrial oxidative phosphorylation is dispensable for survival of CD34(+) chronic myeloid leukemia stem and progenitor cells

Chronic myeloid leukemia (CML) are initiated and sustained by self-renewing malignant CD34(+) stem cells. Extensive efforts have been made to reveal the metabolic signature of the leukemia stem/progenitor cells in genomic, transcriptomic, and metabolomic studies. However, very little proteomic inves...

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Detalles Bibliográficos
Autores principales: Yan, Jin-Song, Yang, Meng-Ying, Zhang, Xue-Hong, Luo, Chen-Hui, Du, Cheng-Kan, Jiang, Yue, Dong, Xuan-Jia, Wang, Zhang-Man, Yang, Li-Xue, Li, Yi-Dong, Xia, Li, Lu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021200/
https://www.ncbi.nlm.nih.gov/pubmed/35444236
http://dx.doi.org/10.1038/s41419-022-04842-5