Cargando…
Insulin receptor activation by proinsulin preserves synapses and vision in retinitis pigmentosa
Synaptic loss, neuronal death, and circuit remodeling are common features of central nervous system neurodegenerative disorders. Retinitis pigmentosa (RP), the leading cause of inherited blindness, is a group of retinal dystrophies characterized by photoreceptor dysfunction and death. The insulin re...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021205/ https://www.ncbi.nlm.nih.gov/pubmed/35444190 http://dx.doi.org/10.1038/s41419-022-04839-0 |