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Investigation of breast cancer microstructure and microvasculature from time-dependent DWI and CEST in correlation with histological biomarkers

We investigated the associations of time-dependent DWI, non-Gaussian DWI, and CEST parameters with histological biomarkers in a breast cancer xenograft model. 22 xenograft mice (7 MCF-7 and 15 MDA-MB-231) were scanned at 4 diffusion times [T(d) = 2.5/5 ms with 11 b-values (0–600 s/mm(2)) and T(d) = ...

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Detalles Bibliográficos
Autores principales: Someya, Yuko, Iima, Mami, Imai, Hirohiko, Yoshizawa, Akihiko, Kataoka, Masako, Isoda, Hiroyoshi, Le Bihan, Denis, Nakamoto, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021220/
https://www.ncbi.nlm.nih.gov/pubmed/35444193
http://dx.doi.org/10.1038/s41598-022-10081-7