Lateral gain is impaired in macular degeneration and can be targeted to restore vision in mice

Macular degeneration is a leading cause of blindness. Treatments to rescue vision are currently limited. Here, we study how loss of central vision affects lateral feedback to spared areas of the human retina. We identify a cone-driven gain control mechanism that reduces visual function beyond the at...

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Detalles Bibliográficos
Autores principales: Rizzi, M., Powell, K., Robinson, M. R., Matsuki, T., Hoke, J., Maswood, R. N., Georgiadis, A., Georgiou, M., Jones, P. R., Ripamonti, C., Nadal-Nicolás, F. M., Michaelides, M., Rubin, G. S., Smith, A. J., Ali, R. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021237/
https://www.ncbi.nlm.nih.gov/pubmed/35444239
http://dx.doi.org/10.1038/s41467-022-29666-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021237/
https://www.ncbi.nlm.nih.gov/pubmed/35444239
http://dx.doi.org/10.1038/s41467-022-29666-x

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