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Tumor-associated macrophage-derived exosomes transmitting miR-193a-5p promote the progression of renal cell carcinoma via TIMP2-dependent vasculogenic mimicry

Previous studies have investigated whether tumor-associated macrophages (TAMs) play tumorigenic and immunosuppressive roles to encourage cancer development, but the role of TAMs in regulating vasculogenic mimicry (VM) in clear-cell renal cell carcinoma (ccRCC) cells has not been completely clarified...

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Detalles Bibliográficos
Autores principales: Liu, Qing, Zhao, Enyang, Geng, Bo, Gao, Shan, Yu, Hongyang, He, Xinyang, Li, Xuedong, Dong, Guanglu, You, Bosen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021253/
https://www.ncbi.nlm.nih.gov/pubmed/35443741
http://dx.doi.org/10.1038/s41419-022-04814-9