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Tension can directly suppress Aurora B kinase-triggered release of kinetochore-microtubule attachments
Chromosome segregation requires sister kinetochores to attach microtubules emanating from opposite spindle poles. Proper attachments come under tension and are stabilized, but defective attachments lacking tension are released, giving another chance for correct attachments to form. This error correc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021268/ https://www.ncbi.nlm.nih.gov/pubmed/35443757 http://dx.doi.org/10.1038/s41467-022-29542-8 |