TRMT6/61A-dependent base methylation of tRNA-derived fragments regulates gene-silencing activity and the unfolded protein response in bladder cancer

RNA modifications are important regulatory elements of RNA functions. However, most genome-wide mapping of RNA modifications has focused on messenger RNAs and transfer RNAs, but such datasets have been lacking for small RNAs. Here we mapped N(1)-methyladenosine (m(1)A) in the cellular small RNA spac...

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Detalles Bibliográficos
Autores principales: Su, Zhangli, Monshaugen, Ida, Wilson, Briana, Wang, Fengbin, Klungland, Arne, Ougland, Rune, Dutta, Anindya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021294/
https://www.ncbi.nlm.nih.gov/pubmed/35444240
http://dx.doi.org/10.1038/s41467-022-29790-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021294/
https://www.ncbi.nlm.nih.gov/pubmed/35444240
http://dx.doi.org/10.1038/s41467-022-29790-8

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