Targeting brain lesions of non-small cell lung cancer by enhancing CCL2-mediated CAR-T cell migration

Metastatic non-small cell lung cancer (NSCLC) remains largely incurable and the prognosis is extremely poor once it spreads to the brain. In particular, in patients with brain metastases, the blood brain barrier (BBB) remains a significant obstacle for the biodistribution of antitumor drugs and immu...

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Detalles Bibliográficos
Autores principales: Li, Hongxia, Harrison, Emily B., Li, Huizhong, Hirabayashi, Koichi, Chen, Jing, Li, Qi-Xiang, Gunn, Jared, Weiss, Jared, Savoldo, Barbara, Parker, Joel S., Pecot, Chad V., Dotti, Gianpietro, Du, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021299/
https://www.ncbi.nlm.nih.gov/pubmed/35443752
http://dx.doi.org/10.1038/s41467-022-29647-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021299/
https://www.ncbi.nlm.nih.gov/pubmed/35443752
http://dx.doi.org/10.1038/s41467-022-29647-0

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