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Glycoprotein nonmetastatic melanoma protein B regulates lysosomal integrity and lifespan of senescent cells

Accumulation of senescent cells in various tissues has been reported to have a pathological role in age-associated diseases. Elimination of senescent cells (senolysis) was recently reported to reversibly improve pathological aging phenotypes without increasing rates of cancer. We previously identifi...

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Detalles Bibliográficos
Autores principales: Suda, Masayoshi, Shimizu, Ippei, Katsuumi, Goro, Hsiao, Chieh Lun, Yoshida, Yohko, Matsumoto, Naomi, Yoshida, Yutaka, Katayama, Akihiro, Wada, Jun, Seki, Masahide, Suzuki, Yutaka, Okuda, Shujiro, Ozaki, Kazuyuki, Nakanishi-Matsui, Mayumi, Minamino, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021310/
https://www.ncbi.nlm.nih.gov/pubmed/35444208
http://dx.doi.org/10.1038/s41598-022-10522-3