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FGF19 Is Coamplified With CCND1 to Promote Proliferation in Lung Squamous Cell Carcinoma and Their Combined Inhibition Shows Improved Efficacy

Lung squamous cell carcinoma (LUSC) remains as a major cause of cancer-associated mortality with few therapeutic options. Continued research on new driver genes is particularly important. FGF19, a fibroblast growth factor, is frequently observed as amplified in human LUSC, which is also associated w...

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Detalles Bibliográficos
Autores principales: Zhang, Yanshuang, Wu, Tingyu, Li, Fan, Cheng, Yirui, Han, Qing, Lu, Xin, Lu, Shun, Xia, Weiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021371/
https://www.ncbi.nlm.nih.gov/pubmed/35463335
http://dx.doi.org/10.3389/fonc.2022.846744