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FGF19 Is Coamplified With CCND1 to Promote Proliferation in Lung Squamous Cell Carcinoma and Their Combined Inhibition Shows Improved Efficacy
Lung squamous cell carcinoma (LUSC) remains as a major cause of cancer-associated mortality with few therapeutic options. Continued research on new driver genes is particularly important. FGF19, a fibroblast growth factor, is frequently observed as amplified in human LUSC, which is also associated w...
Autores principales: | Zhang, Yanshuang, Wu, Tingyu, Li, Fan, Cheng, Yirui, Han, Qing, Lu, Xin, Lu, Shun, Xia, Weiliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021371/ https://www.ncbi.nlm.nih.gov/pubmed/35463335 http://dx.doi.org/10.3389/fonc.2022.846744 |
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