Ubiquitin Carboxyl-Terminal Hydrolase L1 of Cardiomyocytes Promotes Macroautophagy and Proteostasis and Protects Against Post-myocardial Infarction Cardiac Remodeling and Heart Failure

Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) is a deubiquitinase known to play essential roles in the nervous tissue. Myocardial upregulation of UCHL1 was observed in human dilated cardiomyopathy and several animal models of heart disease, but the (patho)physiological significance of UCHL1 in ca...

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Detalles Bibliográficos
Autores principales: Wu, Penglong, Li, Yifan, Cai, Mingqi, Ye, Bo, Geng, Bingchuan, Li, Faqian, Zhu, Hua, Liu, Jinbao, Wang, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021418/
https://www.ncbi.nlm.nih.gov/pubmed/35463782
http://dx.doi.org/10.3389/fcvm.2022.866901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021418/
https://www.ncbi.nlm.nih.gov/pubmed/35463782
http://dx.doi.org/10.3389/fcvm.2022.866901

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