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Endothelial Cell Adhesion Molecules- (un)Attainable Targets for Nanomedicines

Endothelial cell adhesion molecules have long been proposed as promising targets in many pathologies. Despite promising preclinical data, several efforts to develop small molecule inhibitors or monoclonal antibodies (mAbs) against cell adhesion molecules (CAMs) ended in clinical-stage failure. In pa...

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Detalles Bibliográficos
Autores principales: Milošević, Nenad, Rütter, Marie, David, Ayelet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021548/
https://www.ncbi.nlm.nih.gov/pubmed/35463298
http://dx.doi.org/10.3389/fmedt.2022.846065