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Design, Synthesis, and Antitumor Activity Study of All-Hydrocarbon-Stapled B1-Leu Peptides

B1-Leu peptide is a structural optimization compound derived from the lysine- and phenylalanine-rich antimicrobial peptide Cathelicidin-BF. It has shown promising antibacterial and antitumor biological activity. However, linear peptides are not the best choice for novel drug development due to their...

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Detalles Bibliográficos
Autores principales: Su, Zhen, Liu, Chao, Cong, Wei, He, Shipeng, Su, Li, Hu, Honggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021566/
https://www.ncbi.nlm.nih.gov/pubmed/35464194
http://dx.doi.org/10.3389/fchem.2022.840131