Structural Basis of Human Dimeric α-Amino-β-Carboxymuconate-ε-Semialdehyde Decarboxylase Inhibition With TES-1025

Human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) stands at a branch point of the de novo NAD(+) synthesis pathway and plays an important role in maintaining NAD(+) homeostasis. It has been recently identified as a novel therapeutic target for a wide range of diseases, including i...

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Detalles Bibliográficos
Autores principales: Cianci, Michele, Giacchè, Nicola, Cialabrini, Lucia, Carotti, Andrea, Liscio, Paride, Rosatelli, Emiliano, De Franco, Francesca, Gasparrini, Massimiliano, Robertson, Janet, Amici, Adolfo, Raffaelli, Nadia, Pellicciari, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021598/
https://www.ncbi.nlm.nih.gov/pubmed/35463964
http://dx.doi.org/10.3389/fmolb.2022.834700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021598/
https://www.ncbi.nlm.nih.gov/pubmed/35463964
http://dx.doi.org/10.3389/fmolb.2022.834700

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