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Technical Validation and Clinical Utility of an NGS Targeted Panel to Improve Molecular Characterization of Pediatric Acute Leukemia

Development of next-generation sequencing (NGS) has provided useful genetic information to redefine diagnostic, prognostic, and therapeutic strategies for the management of acute leukemia (AL). However, the application in the clinical setting is still challenging. Our aim was to validate the AmpliSe...

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Detalles Bibliográficos
Autores principales: Vicente-Garcés, Clara, Esperanza-Cebollada, Elena, Montesdeoca, Sara, Torrebadell, Montserrat, Rives, Susana, Dapena, José Luis, Català, Albert, Conde, Nuria, Camós, Mireia, Vega-García, Nerea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021638/
https://www.ncbi.nlm.nih.gov/pubmed/35463953
http://dx.doi.org/10.3389/fmolb.2022.854098