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Genetic Modifiers of Thymic Selection and Central Tolerance in Type 1 Diabetes

Type 1 diabetes (T1D) is caused by the T cell-driven autoimmune destruction of insulin-producing cells in the pancreas. T1D served as the prototypical autoimmune disease for genome wide association studies (GWAS) after having already been the subject of many linkage and association studies prior to...

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Detalles Bibliográficos
Autor principal: Kissler, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021641/
https://www.ncbi.nlm.nih.gov/pubmed/35464420
http://dx.doi.org/10.3389/fimmu.2022.889856