ERBB2D16 Expression in HER2 Positive Gastric Cancer Is Associated With Resistance to Trastuzumab

The human epidermal growth factor receptor-2 (ERBB2; formerly HER2)isoform ERBB2ΔEx16 (ERBB2d16) was oncogenic by mediating epithelial-mesenchymal transition (EMT), immune evasion, and resistance cell death to the anti-HER2 (trastuzumab) therapy. However, its physiological implications in gastric ca...

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Detalles Bibliográficos
Autores principales: Wang, Shuo, Zhao, Yuze, Song, Yuguang, Qiao, Guoliang, Di, Yan, Zhao, Jing, Sun, Pingping, Zheng, Huixia, Huang, He, Huang, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021701/
https://www.ncbi.nlm.nih.gov/pubmed/35463314
http://dx.doi.org/10.3389/fonc.2022.855308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021701/
https://www.ncbi.nlm.nih.gov/pubmed/35463314
http://dx.doi.org/10.3389/fonc.2022.855308

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