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High concentrations of the anthelmintic diethylcarbamazine paralyze C. elegans independently of TRP-2
Diethylcarbamazine (DEC) has been used to treat lymphatic filariasis in tropical countries since the 1940s. Its mode of action is still unclear, with several reports suggesting a host immune system-mediated mechanism. We previously demonstrated that DEC causes transient spastic paralysis in the fila...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Caltech Library
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021882/ https://www.ncbi.nlm.nih.gov/pubmed/35622518 http://dx.doi.org/10.17912/micropub.biology.000548 |