Highly Purified Eicosapentaenoic Acid Alleviates the Inflammatory Response and Oxidative Stress in Macrophages during Atherosclerosis via the miR-1a-3p/sFRP1/Wnt/PCP-JNK Pathway

Highly purified eicosapentaenoic acid (EPA) has shown great effects in the prevention of atherosclerosis. In a murine model, it significantly reduced plaque accumulation, lowered plasma lipid levels, and decreased inflammation levels, which was also observed in vitro. Using microRNA sequencing, we i...

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Detalles Bibliográficos
Autores principales: Zang, Tongtong, Chen, Han, Shen, Shutong, Xu, Fei, Wang, Rui, Yin, Jia, Chen, Xiehui, Guan, Min, Shen, Li, Pan, Haobo, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021996/
https://www.ncbi.nlm.nih.gov/pubmed/35464772
http://dx.doi.org/10.1155/2022/9451058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9021996/
https://www.ncbi.nlm.nih.gov/pubmed/35464772
http://dx.doi.org/10.1155/2022/9451058

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