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Mineralocorticoid Receptor Antagonism Prevents the Synergistic Effect of Metabolic Challenge and Chronic Kidney Disease on Renal Fibrosis and Inflammation in Mice

Obesity and/or metabolic diseases are frequently associated with chronic kidney disease and several factors associated with obesity may contribute to proteinuria and extracellular matrix production. Mineralocorticoid receptor antagonists have proven their clinical efficacy in diabetic kidney disease...

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Detalles Bibliográficos
Autores principales: Palacios-Ramirez, Roberto, Lima-Posada, Ixchel, Bonnard, Benjamin, Genty, Marie, Fernandez-Celis, Amaya, Hartleib-Geschwindner, Judith, Foufelle, Fabienne, Lopez-Andres, Natalia, Bamberg, Krister, Jaisser, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022039/
https://www.ncbi.nlm.nih.gov/pubmed/35464084
http://dx.doi.org/10.3389/fphys.2022.859812