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Australian Aboriginal Otitis-Prone Children Produce High-Quality Serum IgG to Putative Nontypeable Haemophilus influenzae Vaccine Antigens at Lower Titres Compared to Non-Aboriginal Children

BACKGROUND: Nontypeable Haemophilus influenzae (NTHi) is the most common bacterial otopathogen associated with otitis media (OM). NTHi persists in biofilms within the middle ears of children with chronic and recurrent OM. Australian Aboriginal children suffer exceptionally high rates of chronic and...

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Detalles Bibliográficos
Autores principales: Clark, Sharon L., Seppanen, Elke J., Kirkham, Lea-Ann S., Novotny, Laura A., Bakaletz, Lauren O., Cripps, Allan W., Corscadden, Karli, Coates, Harvey, Vijayasekaran, Shyan, Richmond, Peter C., Thornton, Ruth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022120/
https://www.ncbi.nlm.nih.gov/pubmed/35463651
http://dx.doi.org/10.3389/fcimb.2022.767083