A Low Membrane Hsp70 Expression in Tumor Cells With Impaired Lactate Metabolism Mediates Radiosensitization by NVP-AUY922

As overexpression and membrane localization of stress proteins together with high lactate levels promote radioresistance in tumor cells, we studied the effect of the Hsp90 inhibitor NVP-AUY922 on the cytosolic and membrane expression of heat shock proteins (HSPs) and radiosensitivity in murine melan...

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Detalles Bibliográficos
Autores principales: Schwab, Melissa, Multhoff, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022188/
https://www.ncbi.nlm.nih.gov/pubmed/35463341
http://dx.doi.org/10.3389/fonc.2022.861266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9022188/
https://www.ncbi.nlm.nih.gov/pubmed/35463341
http://dx.doi.org/10.3389/fonc.2022.861266

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